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Search Results for " urinary tract infections "

35

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T8133	SulfadiMethoxine sodium	Anti-infection; Antibacterial; Antibiotic	Microbiology/Virology
	SulfadiMethoxine sodium 是一种磺胺类抗生素，可研究由多种感染引起的疾病。
T1078	Sulfadimethoxine Sulphadimethoxine,磺胺二甲氧嗪	Antibacterial; Antibiotic	Microbiology/Virology
	Sulfadimethoxine (Sulphadimethoxine) 是一种磺胺类抗生素，用于多种感染引起的疾病的研究。
T16789	Rosoxacin 罗索沙星,Acrosoxacin	Antibacterial; Antibiotic	Microbiology/Virology
	Rosoxacin (Acrosoxacin) 是具有口服活性的喹诺酮类抗生素，具有广谱的抗菌活性，抑制革兰氏阴性菌，包括淋病奈瑟氏球菌(MIC90=0.03 mg/ml)。它在尿路感染中有应用的潜能。
T0116	Balofloxacin	DNA gyrase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Balofloxacin 是一种具有口服活性的氟喹诺酮类抗生素，可通过干扰 DNA 促旋酶来抑制细菌 DNA 的合成，对革兰氏阴性，革兰氏阳性和厌氧菌具有广谱抗菌活性。它可研究呼吸道，肠道和泌尿道感染。
T0274	Cinoxacin 西诺沙星,Compound 64716	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Cinoxacin (Compound 64716) 是一种喹诺酮类的合成抗生素, 与Oxolinic acid 和 Nalidixic acid 活性相似。
T1233	Oxolinic acid Emyrenil,Nidantin,NSC 110364,恶喹酸,Dioxacin,Urinox	Dopamine Receptor; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Microbiology/Virology; Neuroscience
	Oxolinic acid (Nidantin) 是一种抗生素，对革兰氏阴性菌和革兰氏阳性菌均有效，可研究急性和慢性尿路感染。它是一种 DNA/RNA 合成抑制剂，也是一种多巴胺摄取抑制剂，能刺激小鼠的活跃过度。
T5189	Omadacycline PTK 0796,Amadacycline	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Omadacycline (Amadacycline) 是一种具有口服活性的氨基甲基环素抗菌剂，是四环素类抗生素。它与 30S 核糖体亚基结合，抑制细菌蛋白质合成。它可用于研究急性细菌性皮肤和皮肤结构感染，感染性肺炎和尿路感染。
T0703	Flavoxate hydrochloride Flavoxate HCl,盐酸黄酮哌酯,NSC-114649,DW61,Rec-7-0040	AChR	Neuroscience
	Flavoxate hydrochloride (DW61) 是一种毒蕈碱受体 AChR 拮抗剂， IC50为 12.2 μM。
T4273	Furagin F-35,Akritoin,Furazidine,NF-416,呋喃烯啶,Furazidin	Antibacterial	Microbiology/Virology
	Furagin (Furazidine) 是 nitrofurantoin 类似物，有抗菌活性，用于尿路感染。
T19794	Temafloxacin 替马沙星,Omniflox	Antibiotic	Microbiology/Virology
	Temafloxacin (Omniflox) 是一种喹诺酮类广谱抗菌剂，对革兰氏阳性菌、革兰氏阴性菌和厌氧菌均有效。
T0087L	Sulfacetamide sodium Sulamyd sodium,磺乙酰胺钠盐,磺胺醋酰钠	Antibacterial; Antibiotic; Autophagy	Autophagy; Microbiology/Virology
	Sulfacetamide sodium (Sulamyd sodium) 是磺胺类抗感染剂，可局部用于口服治疗尿路感染和皮肤感染。
T0026	Sulfalene 磺胺林,Sulfalene(SMPZ),Sulfalen,SMP2,Butadiene sulfone,AS-18908,Sulfametopyrazine,3-Sulfolene	Antibacterial; Antibiotic; Parasite; Autophagy	Autophagy; Microbiology/Virology
	Sulfalene (SMP2) 是一种长效磺胺类抗生素，用于治疗慢性支气管炎、尿路感染和疟疾。
T0748	Sulfameter 5-Methoxysulfadiazine,Sulfametoxydiazine,磺胺对甲氧嘧啶	DHFR; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Sulfameter (Sulfametoxydiazine) 是一种长效磺胺类抗生素，具有抗菌活性。它可研究尿路感染和麻风病。
T2184	Sulfachloropyridazine Sulfachlorpyridazine,磺胺二甲基嘧啶	Antibacterial; Antibiotic	Microbiology/Virology
	Sulfachloropyridazine (Sulfachlorpyridazine) 是一种广谱磺酰胺，抑制革兰氏阳性和革兰氏阴性好氧细菌的生长。
T0400	Nitroxoline 5-Nitro-8-quinolinol,8-Hydroxy-5-nitroquinoline,5-Nitro-8-hydroxyquinoline,5-nitroquinolin-8-ol,硝羟喹啉	Antibacterial; Antibiotic; Autophagy	Autophagy; Microbiology/Virology
	Nitroxoline (5-nitroquinolin-8-ol) 是一种抗生素，防治生物膜感染。它通过从生物膜基质螯合Fe2+和Zn2+离子而发挥作用。
T0170	Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (9CI) phosphonomycin calcium,Fosfomycin calcium,磷霉素钙,phosphomycin calcium	Antibiotic	Microbiology/Virology
	Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (9CI) (phosphonomycin calcium)是一种抗生素，用于治疗敏感菌株引起的尿路感染和肠道感染。
T8134	Cefathiamidine	Antibacterial; Antibiotic	Microbiology/Virology
	Cefathiamidine 是一种头孢菌素抗菌剂，可研究由易感细菌引起的感染，还可用于呼吸道、肝脏、五官感觉、尿路感染以及心内膜炎和败血症的研究。
T21369	Mecillinam Amdinocillin,Mecillinamum,Hexacillin,美西林,Coactin,Penicillin HX	Antibacterial	Microbiology/Virology
	Mecillinam (Hexacillin) 是一种有抗革兰氏阴性菌活性的 β 内酰胺类广谱抗生素。
T26974	Cefetamet Hydrochloride Cefetamet HCl,Cefetamet
	Cefetamet is a potent antibiotic to treat respiratory and urinary tract infections.
T30790	Ceftolozane sulfate FR 264205,FR264205,FR-264205
	Ceftolozane Sulfate may be used to treat urinary tract infections.
T68999	Cefonicid (free base)
	Cefonicid (free base) is a second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
T26950	Carfecillin Sodium Carbenicillin Phenyl Sodium,Uticillin,BRL-3475,BRL3475,BRL 3475
	Carfecillin Sodium is the phenyl ester of Carbenicillin, it is broken down in the intestinal mucosa to the active antibacterial upon oral administration. Carfecillin Sodiumis used for urinary tract infections.
T68817	Cefonicid monosodium
	Cefonicid monosodium is the salt form of Cefonicid (free base), a second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
T30737	Carbavance Meropenem/vaborbactam,Vabomere
	Carbavance, a mixture of Meropenham and Vaborbactam, is intended for adults with complex urinary tract infections (cUTI), including pyelonephritis, a kidney infection caused by certain bacteria.
T60260	Phenazopyridine
	Phenazopyridine 对尿路具有局部镇痛作用，常用于缓解泌尿道感染、手术或泌尿道损伤引起的疼痛、刺激、不适或尿急。
T11289	Finafloxacin	Others	Others
	Finafloxacin, a fluoroquinolone antimicrobial agent from a new 8-cyano subclass, is most effective in slightly acidic environments (pH 5.0-6.0), a condition where other fluoroquinolones typically reduce in activity. It selectively targets bacterial type II topoisomerases, such as DNA gyrase and DNA topoisomerase IV, making it suitable for treating serious bacterial infections particularly in acidic contexts, including urinary tract infections (UTIs) and Helicobacter pylori infections.
T60569	Sulfametrole
	Sulfametrole 是具有口服活性的抗菌剂，可用于传染病相关的研究，如艾滋病毒、严重肺炎和尿路感染。
T39862	Trimethoprim lactate
	Trimethoprim lactic is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim lactic is active against a wide range of Gram-positive and Gram-negative aerobic bacteria . Trimethoprim lactic has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment.
T35851	Etzadroxil Ethyl 2-Ethylbutyrate	Antibacterial	Microbiology/Virology
	Etzadroxil (Ethyl 2-Ethylbutyrate) 是一种可口服且具有挥发性的酯化物。Etzadroxil 具有广谱的抗菌活性，可用于治疗由多重耐药细菌引起的尿路感染。
T75286	Sitafloxacin hydrochloride
	Sitafloxacin (DU6859a) hydrochloride 是一款有效的口服活性氟喹诺酮类抗生素，它对广泛的革兰氏阳性细菌、革兰氏阴性细菌（包括厌氧菌）及非典型病原体都显示出抗菌活性。该化合物主要用于研究呼吸道感染和尿路感染。
T36537	Nitrofurantoin-13C3 Nitrofurantoin-13C3
	Nitrofurantoin-13C3is intended for use as an internal standard for the quantification of nitrofurantoin by GC- or LC-MS. Nitrofurantoin is a nitrofuran antibiotic.1In vivo, nitrofurantoin (25-100 mg/kg) reducesE. colireplication and abscess formation in the renal medulla of infected rats in a dose-dependent manner. It prevents kidney and bladder infection in rats following bladder inoculation with clinical isolates ofP. mirabilis. Nitrofurantoin also prevents alkalization of urine, as well as ca...
T75287	Sitafloxacin monohydrate
	Sitafloxacin monohydrate (DU6859a) 是一种具有广谱的抗菌活性，并对多种革兰氏阳性和革兰氏阴性细菌（包括厌氧菌）以及非典型病原体有效的口服活性氟喹诺酮类抗生素。它主要用于研究呼吸道感染和尿路感染。
T75291	Trimethoprim hydrochloride
	Trimethoprim hydrochloride 是一种口服活性的抑菌抗生素，同时也是二氢叶酸还原酶抑制剂。它对多种革兰氏阳性及革兰氏阴性需氧细菌有效。用于尿路感染、志贺氏菌病和肺孢子菌肺炎的研究。与锌联合使用时，可抑制甲型流感病毒对鸡胚的感染。
T75296	Pazufloxacin
	Pazufloxacin (T-3761)是氟喹诺酮类广谱抗生素。
T36021	Flumequine-13C3 Flumequine-13C3
	Flumequine-13C3is intended for use as an internal standard for the quantification of flumequine by GC- or LC-MS. Flumequine is a fluoroquinolone antibiotic.1It is active againstS. aureus, S. pyogenes, B. subtilis, E. coli, P. aeruginosa, S. faecalis, andK. pneumoniae(MICs = 1-100 μg/ml). Flumequine is also active against field isolates of B. hyodysenteriae (MICs = 6.25-200 μg/ml).2It inhibits DNA gyrase, disrupting supercoiling of bacterial DNA to block transcription and replication.3In vivo, fl...

化合物

SulfadiMethoxine sodium

Cat.No: T8133

Target: Anti-infection, Antibacterial, Antibiotic

Sulfadimethoxine

Cat.No: T1078

Synonym: Sulphadimethoxine,磺胺二甲氧嗪

Target: Antibacterial, Antibiotic

Cat.No: T16789

Synonym: 罗索沙星,Acrosoxacin

Target: Antibacterial, Antibiotic

Cat.No: T0116

Target: DNA gyrase, Antibacterial, Antibiotic

Cat.No: T0274

Synonym: 西诺沙星,Compound 64716

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T1233

Synonym: Emyrenil,Nidantin,NSC 110364,恶喹酸,Dioxacin,Urinox

Target: Dopamine Receptor, DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T5189

Synonym: PTK 0796,Amadacycline

Target: ribosome, Antibacterial, Antibiotic

Flavoxate hydrochloride

Cat.No: T0703

Synonym: Flavoxate HCl,盐酸黄酮哌酯,NSC-114649,DW61,Rec-7-0040

Target: AChR

Cat.No: T4273

Synonym: F-35,Akritoin,Furazidine,NF-416,呋喃烯啶,Furazidin

Target: Antibacterial

Cat.No: T19794

Synonym: 替马沙星,Omniflox

Target: Antibiotic

Sulfacetamide sodium

Cat.No: T0087L

Synonym: Sulamyd sodium,磺乙酰胺钠盐,磺胺醋酰钠

Target: Antibacterial, Antibiotic, Autophagy

Cat.No: T0026

Synonym: 磺胺林,Sulfalene(SMPZ),Sulfalen,SMP2,Butadiene sulfone,AS-18908,Sulfametopyrazine,3-Sulfolene

Target: Antibacterial, Antibiotic, Parasite, Autophagy

Cat.No: T0748

Synonym: 5-Methoxysulfadiazine,Sulfametoxydiazine,磺胺对甲氧嘧啶

Target: DHFR, Antibacterial, Antibiotic

Sulfachloropyridazine

Cat.No: T2184

Synonym: Sulfachlorpyridazine,磺胺二甲基嘧啶

Target: Antibacterial, Antibiotic

Cat.No: T0400

Synonym: 5-Nitro-8-quinolinol,8-Hydroxy-5-nitroquinoline,5-Nitro-8-hydroxyquinoline,5-nitroquinolin-8-ol,硝羟喹啉

Target: Antibacterial, Antibiotic, Autophagy

Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (9CI)

Cat.No: T0170

Synonym: phosphonomycin calcium,Fosfomycin calcium,磷霉素钙,phosphomycin calcium

Target: Antibiotic

Cat.No: T8134

Target: Antibacterial, Antibiotic

Cat.No: T21369

Synonym: Amdinocillin,Mecillinamum,Hexacillin,美西林,Coactin,Penicillin HX

Target: Antibacterial

Cefetamet Hydrochloride

Cat.No: T26974

Synonym: Cefetamet HCl,Cefetamet

Ceftolozane sulfate

Cat.No: T30790

Synonym: FR 264205,FR264205,FR-264205

Cefonicid (free base)

Cat.No: T68999

Carfecillin Sodium

Cat.No: T26950

Synonym: Carbenicillin Phenyl Sodium,Uticillin,BRL-3475,BRL3475,BRL 3475

Cefonicid monosodium

Cat.No: T68817

Cat.No: T30737

Synonym: Meropenem/vaborbactam,Vabomere

Phenazopyridine

Cat.No: T60260

Cat.No: T11289

Target: Others

Cat.No: T60569

Trimethoprim lactate

Cat.No: T39862

Cat.No: T35851

Synonym: Ethyl 2-Ethylbutyrate

Target: Antibacterial

Sitafloxacin hydrochloride

Cat.No: T75286

Nitrofurantoin-13C3

Cat.No: T36537

Synonym: Nitrofurantoin-13C3

Sitafloxacin monohydrate

Cat.No: T75287

Trimethoprim hydrochloride

Cat.No: T75291

Cat.No: T75296

Flumequine-13C3

Cat.No: T36021

Synonym: Flumequine-13C3

Cat. No.	Product Name	Target	Signaling Pathways
T1153	Trimethoprim NIH 204,BW 56-72,甲氧苄啶,NSC-106568	DHFR; DNA/RNA Synthesis; Antifolate; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Trimethoprim (NSC-106568) 是抑菌抗生素，也是具有口服活性的二氢叶酸还原酶抑制剂。它对多种革兰氏阳性和革兰氏阴性需氧细菌具有活性，可用于尿路感染，肺孢子菌肺炎和志贺氏菌病的研究。
T16542	Piromidic acid 吡咯酸,吡乙酸三氮萘	Antibacterial; Antibiotic	Microbiology/Virology
	Piromidic acid 是一种抗菌剂。它对革兰氏阴性菌和葡萄球菌具有活性，可研究肠道，泌尿和胆道感染。
T6567	Levofloxacin Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Levofloxacin (Fluoroquinolone) 是合成的氟喹诺酮类抗生素，有抑制细菌DNA 旋转酶的超螺旋活性的作用，能阻止DNA 复制。

天然产物

Cat.No: T1153

Synonym: NIH 204,BW 56-72,甲氧苄啶,NSC-106568

Target: DHFR, DNA/RNA Synthesis, Antifolate, Antibacterial, Antibiotic

Cat.No: T16542

Synonym: 吡咯酸,吡乙酸三氮萘

Target: Antibacterial, Antibiotic

Cat.No: T6567

Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin

Target: Topoisomerase, Antibacterial, Antibiotic

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